If you want to participate in any present or future clinical studies, please get in touch with the study coordinator(s) to express your interest.
‎
Ongoing clinical studies:
Efficacy and safety of autologous, mobilized, non-expanded CD133+ cells to treat patients with Asherman’s syndrome: a prospective, multicenter, phase I/II clinical trial
“Asherman Therapy” is conducting a clinical study to develop cell therapy-based treatments for Asherman’s syndrome.
This multicenter study, conducted by the Hospital Universitari de la Vall Hebron, the Banc de Sang i Teixits (BST), and the Pilar and Quiron Clinics of the Quironsalud Group, is coordinated by Dr. Xavier Santamaria, the Scientific Director of Asherman Therapy.
The study has been approved by the Vall Hebron University Hospital’s Drug Research Ethics Committee and the Spanish Agency for Medicines and Health Products (AEMPS). In addition, this study has been previously evaluated with scientific advice by the European Medicines Agency (EMA).
If you have been diagnosed with moderate or severe Asherman’s syndrome and wish to request more information on how to participate, please contact Asherman Therapy at the following email address: entire.study@ashermantherapy.com. The study investigators will provide you with as much information as needed without obligation and evaluate your eligibility to participate.
Simply contacting or responding to this announcement does not commit you to participate but only expresses your desire to obtain more information regarding this study.
Molecular transcriptomics of the endometrium in patients with repeated implantation failure by RNA sequencing at the single cell level: a prospective case-control study
The Carlos Simon Foundation is conducting a clinical study to learn more about the molecular mechanisms involved in repeated implantation failure (RIF) and the possible impact of the microbial flora in the uterine cavity by comparing fertile patients with those diagnosed with RIF.
This study, coordinated by Dr. Carlos Simon of the Carlos Simon Foundation and carried out at the Fertty Clinic by Dr. Juan Jose Espinos and Dr. Miguel Angel Checa, has been approved by the Ethics Committee of the Parc de Salut del Mar.
If you wish to request more information about possible participation, please use the following email: recruitment.patients@outlook.com. The study investigators will provide you with as much information as needed without any obligation and will evaluate if you meet the requirements to participate.
Simply contacting or responding to this announcement does not commit you to participate but only expresses your desire to obtain more information regarding this study.
Decoding the endometrial niche of adenomyosis at single-cell resolution
The Carlos Simon Foundation is conducting a clinical study to improve our understanding of endometrial adenomyosis, a disease with a proposed relationship with various reproductive problems.
This study, coordinated by Dr. Carlos Simon of the Carlos Simon Foundation and carried out at the 12 de Octubre Hospital in Madrid by Dr. Magdalena Abad, has the approval of the Ethics Committee for Research with Medicine of the 12 de Octubre Hospital in Madrid.
If you wish to request more information about possible participation, please use the following email: recruitment.patients@outlook.com. The study investigators will provide you with as much information as needed without any obligation and will evaluate if you meet the requirements to participate.
Simply contacting or responding to this announcement does not commit you to participate but only expresses your desire to obtain more information regarding this study.
Prospective multicenter national biomedical cohort study of patients with surgical indications of suspected ovarian cancer
The Carlos Simon Foundation and INCLIVA are conducting a clinical study to analyze tumor tissue and peripheral blood for the early diagnosis of ovarian tumors in patients with surgical indications of suspected ovarian cancer.
This study is coordinated by Dr. Carlos Simon and Dr. Aymara Mas of the Carlos Simon Foundation and INCLIVA and is carried out in the Hospital Universitario y Politecnico La Fe of Valencia, Hospital Clinico Universitario Virgen de la Arrixaca of Murcia, Hospital Universitario Quironsalud of Madrid and Hospital IMED of Valencia by doctors Santiago Domingo, Victor Lago, Anibal Nieto, Sara Iacoponi and Lucas Minig. This study has the approval of the Ethics Committee of the Investigation with Medicines of the Hospital Universitario y Politecnico La Fe of Valencia.
If you wish to request more information about possible participation, please use the following email: recruitment.patients@outlook.com. The study investigators will provide you with as much information as needed without any obligation and will evaluate if you meet the requirements to participate.
Simply contacting or responding to this announcement does not commit you to participate but only expresses your desire to obtain more information regarding this study.
Prospective clinical study for the implementation of a molecular screening for the early detection of preeclampsia in the first trimester of pregnancy
“iPremom” is conducting a clinical study on pregnant women in the first trimester of pregnancy to develop a screening tool to identify pregnant women at risk of developing preeclampsia or other relevant obstetric pathologies at early stages.
This study, coordinated by Dr. Carlos Simon and Dr. Tamara Garrido of the Carlos Simon Foundation, has the approval of the Ethics Committee for Research with Medicines of the Hospital Universitario y Politecnico La Fe of Valencia and is conducted in Spanish hospitals.
If you wish to request more information about possible participation, please contact iPremom at the following email: premom.study@ipremom.com. The study investigators will provide you with as much information as needed without any obligation and will evaluate if you meet the requirements to participate.
Simply contacting or responding to this announcement does not commit you to participate but only expresses your desire to obtain more information regarding this study.
Lifelong obesity prevention through early risk factors identification, prognosis, and intervention
The Carlos Simon Foundation is conducting a clinical study to define RNA molecules (microRNAs) generated in the endometrium (the tissue that lines the uterus) in women with obesity in the hope of understanding if gene expression becomes modified in the embryo and if the affected child suffers from obesity in adulthood.
This study is coordinated by Drs. Carlos Simon and Felip Vilella of the Carlos Simon Foundation and carried out at the Hospital Universitario y Politecnico La Fe of Valencia by Dr. Alba Roca Prats and Dr. Rogelio Monfort Ortiz. The study has the approval of the Ethics Committee for Research with Medicines of the Hospital Universitario y Politecnico La Fe of Valencia.
If you wish to request more information about possible participation, please use the following email: recruitment.patients@outlook.com. The study investigators will provide you with as much information as needed without any obligation and will evaluate if you meet the requirements to participate.
Simply contacting or responding to this announcement does not commit you to participate but only expresses your desire to obtain more information regarding this study.
Observational, prospective pilot study for the detection of intrapartum vaginal Streptococcus agalactiae using the DETECTR method as a proof of concept for the development of a rapid diagnostic test for group B Streptococcus
The Carlos Simon Foundation is conducting a clinical study to evaluate whether the development of a rapid test for group B Streptococcus detection in vaginal samples is feasible, as routine 48-hour group B Streptococcus culture is currently performed between 35-37 weeks of pregnancy or by assessing clinical risk factors based on clinical history.
This study, coordinated by Dr. Carlos Simon and Dr. Inmaculada Moreno of the Carlos Simon Foundation and carried out at the Hospital Universitario y Politecnico La Fe de Valencia by Dr. Rogelio Monfort, has the approval of the Ethics Committee for Research with Medicines of the Hospital Universitario y Politecnico La Fe de Valencia.
If you wish to request more information about possible participation, please use the following email: recruitment.patients@outlook.com. The study investigators will provide you with as much information as needed without any obligation and will evaluate if you meet the requirements to participate.
Simply contacting or responding to this announcement does not commit you to participate but only expresses your desire to obtain more information regarding this study.
Biometric study for human endometrial stem cell identification and demonstration of their regenerative capacity through organoids (in vitro) and xenografts (in vivo) development in a murine model
The Carlos Simon Foundation is conducting a clinical study to identify which cells are capable of regenerating the endometrium after its loss in order to develop new therapies to reverse the incurability of these pathologies.
This study, coordinated by Dr. Carlos Simon of the Carlos Simon Foundation and carried out at the QuironSalud Barcelona and El Pilar Quiron Barcelona hospitals by doctors Juan Jose Torrent and Ramon Aurell, has the approval of the Ethics Committee for Research with Medicines of the Quironsalud Catalunya Hospital Group.
If you wish to request more information about possible participation, please use the following email: recruitment.patients@outlook.com. The study investigators will provide you with as much information as needed without any obligation and will evaluate if you meet the requirements to participate.
Simply contacting or responding to this announcement does not commit you to participate but only expresses your desire to obtain more information regarding this study.
Prospective observational study for the isolation and characterization of the mitochondrial DNA content of extracellular vesicles secreted by the human endometrium into the endometrial fluid
The tissue that lines the uterus (called the endometrium) is responsible for the initiation and maintenance of pregnancy. Previous studies have shown that endometrial cells secrete DNA molecules that are internalized by the embryo before it implants in the uterus.
The Carlos Simon Foundation is conducting a clinical study to demonstrate that these DNA molecules help the embryo generate the energy necessary to initiate pregnancy in volunteer women of reproductive age enrolled in the oocyte donation program of the clinic.
This study, coordinated by Dr. Carlos Simon of the Carlos Simon Foundation and carried out at the Fertty Clinic in Barcelona by doctors Miguel Angel Checa and Juan Jose Espinos, has the approval of the Medicines Research Ethics Committee of Parc de Salut Mar.
If you wish to request more information about possible participation, please use the following email: recruitment.patients@outlook.com. The study investigators will provide you with as much information as needed without any obligation and will evaluate if you meet the requirements to participate.
Simply contacting or responding to this announcement does not commit you to participate but only expresses your desire to obtain more information regarding this study.
If you are a healthcare professional interested in collaborating with us, please email info@carlossimonfoundation.com with your proposal. We would like to know more about how you could contribute to our work.
If you are interested in donating to support our research, please email info@carlossimonfoundation.com, and one of our representatives will respond to your inquiry promptly.
If you want to learn about any present or future clinical studies, please get in touch with the study coordinator(s) to express your interest.
‎
Ongoing clinical studies:
Efficacy and safety of autologous, mobilized, non-expanded CD133+ cells to treat patients with Asherman’s syndrome: a prospective, multicenter, phase I/II clinical trial
“Asherman Therapy” is conducting a clinical study to develop cell therapy-based treatments for Asherman’s syndrome.
This multicenter study, conducted by the Hospital Universitari de la Vall Hebron, the Banc de Sang i Teixits (BST), and the Pilar and Quiron Clinics of the Quironsalud Group, is coordinated by Dr. Xavier Santamaria, the Scientific Director of Asherman Therapy.
The study has been approved by the Vall Hebron University Hospital’s Drug Research Ethics Committee and the Spanish Agency for Medicines and Health Products (AEMPS). In addition, this study has been previously evaluated with scientific advice by the European Medicines Agency (EMA).
If you have been diagnosed with moderate or severe Asherman’s syndrome and wish to request more information on how to participate, please contact Asherman Therapy at the following email address: entire.study@ashermantherapy.com. The study investigators will provide you with as much information as needed without obligation and evaluate your eligibility to participate.
Simply contacting or responding to this announcement does not commit you to participate but only expresses your desire to obtain more information regarding this study.
Molecular transcriptomics of the endometrium in patients with repeated implantation failure by RNA sequencing at the single cell level: a prospective case-control study
The Carlos Simon Foundation is conducting a clinical study to learn more about the molecular mechanisms involved in repeated implantation failure (RIF) and the possible impact of the microbial flora in the uterine cavity by comparing fertile patients with those diagnosed with RIF.
This study, coordinated by Dr. Carlos Simon of the Carlos Simon Foundation and carried out at the Fertty Clinic by Dr. Juan Jose Espinos and Dr. Miguel Angel Checa, has been approved by the Ethics Committee of the Parc de Salut del Mar.
If you wish to request more information about possible participation, please use the following email: recruitment.patients@outlook.com. The study investigators will provide you with as much information as needed without any obligation and will evaluate if you meet the requirements to participate.
Simply contacting or responding to this announcement does not commit you to participate but only expresses your desire to obtain more information regarding this study.
Decoding the endometrial niche of adenomyosis at single-cell resolution
The Carlos Simon Foundation is conducting a clinical study to improve our understanding of endometrial adenomyosis, a disease with a proposed relationship with various reproductive problems.
This study, coordinated by Dr. Carlos Simon of the Carlos Simon Foundation and carried out at the 12 de Octubre Hospital in Madrid by Dr. Magdalena Abad, has the approval of the Ethics Committee for Research with Medicine of the 12 de Octubre Hospital in Madrid.
If you wish to request more information about possible participation, please use the following email: recruitment.patients@outlook.com. The study investigators will provide you with as much information as needed without any obligation and will evaluate if you meet the requirements to participate.
Simply contacting or responding to this announcement does not commit you to participate but only expresses your desire to obtain more information regarding this study.
Prospective multicenter national biomedical cohort study of patients with surgical indications of suspected ovarian cancer
The Carlos Simon Foundation and INCLIVA are conducting a clinical study to analyze tumor tissue and peripheral blood for the early diagnosis of ovarian tumors in patients with surgical indications of suspected ovarian cancer.
This study is coordinated by Dr. Carlos Simon and Dr. Aymara Mas of the Carlos Simon Foundation and INCLIVA and is carried out in the Hospital Universitario y Politecnico La Fe of Valencia, Hospital Clinico Universitario Virgen de la Arrixaca of Murcia, Hospital Universitario Quironsalud of Madrid and Hospital IMED of Valencia by doctors Santiago Domingo, Victor Lago, Anibal Nieto, Sara Iacoponi and Lucas Minig. This study has the approval of the Ethics Committee of the Investigation with Medicines of the Hospital Universitario y Politecnico La Fe of Valencia.
If you wish to request more information about possible participation, please use the following email: recruitment.patients@outlook.com. The study investigators will provide you with as much information as needed without any obligation and will evaluate if you meet the requirements to participate.
Simply contacting or responding to this announcement does not commit you to participate but only expresses your desire to obtain more information regarding this study.
Prospective clinical study for the implementation of a molecular screening for the early detection of preeclampsia in the first trimester of pregnancy
“iPremom” is conducting a clinical study on pregnant women in the first trimester of pregnancy to develop a screening tool to identify pregnant women at risk of developing preeclampsia or other relevant obstetric pathologies at early stages.
This study, coordinated by Dr. Carlos Simon and Dr. Tamara Garrido of the Carlos Simon Foundation, has the approval of the Ethics Committee for Research with Medicines of the Hospital Universitario y Politecnico La Fe of Valencia and is conducted in Spanish hospitals.
If you wish to request more information about possible participation, please contact iPremom at the following email: premom.study@ipremom.com. The study investigators will provide you with as much information as needed without any obligation and will evaluate if you meet the requirements to participate.
Simply contacting or responding to this announcement does not commit you to participate but only expresses your desire to obtain more information regarding this study.
Lifelong obesity prevention through early risk factors identification, prognosis, and intervention
The Carlos Simon Foundation is conducting a clinical study to define RNA molecules (microRNAs) generated in the endometrium (the tissue that lines the uterus) in women with obesity in the hope of understanding if gene expression becomes modified in the embryo and if the affected child suffers from obesity in adulthood.
This study is coordinated by Drs. Carlos Simon and Felip Vilella of the Carlos Simon Foundation and carried out at the Hospital Universitario y Politecnico La Fe of Valencia by Dr. Alba Roca Prats and Dr. Rogelio Monfort Ortiz. The study has the approval of the Ethics Committee for Research with Medicines of the Hospital Universitario y Politecnico La Fe of Valencia.
If you wish to request more information about possible participation, please use the following email: recruitment.patients@outlook.com. The study investigators will provide you with as much information as needed without any obligation and will evaluate if you meet the requirements to participate.
Simply contacting or responding to this announcement does not commit you to participate but only expresses your desire to obtain more information regarding this study.
Observational, prospective pilot study for the detection of intrapartum vaginal Streptococcus agalactiae using the DETECTR method as a proof of concept for the development of a rapid diagnostic test for group B Streptococcus
The Carlos Simon Foundation is conducting a clinical study to evaluate whether the development of a rapid test for group B Streptococcus detection in vaginal samples is feasible, as routine 48-hour group B Streptococcus culture is currently performed between 35-37 weeks of pregnancy or by assessing clinical risk factors based on clinical history.
This study, coordinated by Dr. Carlos Simon and Dr. Inmaculada Moreno of the Carlos Simon Foundation and carried out at the Hospital Universitario y Politecnico La Fe de Valencia by Dr. Rogelio Monfort, has the approval of the Ethics Committee for Research with Medicines of the Hospital Universitario y Politecnico La Fe de Valencia.
If you wish to request more information about possible participation, please use the following email: recruitment.patients@outlook.com. The study investigators will provide you with as much information as needed without any obligation and will evaluate if you meet the requirements to participate.
Simply contacting or responding to this announcement does not commit you to participate but only expresses your desire to obtain more information regarding this study.
Biometric study for human endometrial stem cell identification and demonstration of their regenerative capacity through organoids (in vitro) and xenografts (in vivo) development in a murine model
The Carlos Simon Foundation is conducting a clinical study to identify which cells are capable of regenerating the endometrium after its loss in order to develop new therapies to reverse the incurability of these pathologies.
This study, coordinated by Dr. Carlos Simon of the Carlos Simon Foundation and carried out at the QuironSalud Barcelona and El Pilar Quiron Barcelona hospitals by doctors Juan Jose Torrent and Ramon Aurell, has the approval of the Ethics Committee for Research with Medicines of the Quironsalud Catalunya Hospital Group.
If you wish to request more information about possible participation, please use the following email: recruitment.patients@outlook.com. The study investigators will provide you with as much information as needed without any obligation and will evaluate if you meet the requirements to participate.
Simply contacting or responding to this announcement does not commit you to participate but only expresses your desire to obtain more information regarding this study.
Prospective observational study for the isolation and characterization of the mitochondrial DNA content of extracellular vesicles secreted by the human endometrium into the endometrial fluid
The tissue that lines the uterus (called the endometrium) is responsible for the initiation and maintenance of pregnancy. Previous studies have shown that endometrial cells secrete DNA molecules that are internalized by the embryo before it implants in the uterus.
The Carlos Simon Foundation is conducting a clinical study to demonstrate that these DNA molecules help the embryo generate the energy necessary to initiate pregnancy in volunteer women of reproductive age enrolled in the oocyte donation program of the clinic.
This study, coordinated by Dr. Carlos Simon of the Carlos Simon Foundation and carried out at the Fertty Clinic in Barcelona by doctors Miguel Angel Checa and Juan Jose Espinos, has the approval of the Medicines Research Ethics Committee of Parc de Salut Mar.
If you wish to request more information about possible participation, please use the following email: recruitment.patients@outlook.com. The study investigators will provide you with as much information as needed without any obligation and will evaluate if you meet the requirements to participate.
Simply contacting or responding to this announcement does not commit you to participate but only expresses your desire to obtain more information regarding this study.
If you are a healthcare professional interested in collaborating with us, please email info@carlossimonfoundation.com with your proposal. We would like to know more about how you could contribute to our work.
If you are interested in donating to support our research, please email info@carlossimonfoundation.com, and one of our representatives will respond to your inquiry promptly.